{"id":4068,"date":"2021-12-10T13:47:00","date_gmt":"2021-12-10T12:47:00","guid":{"rendered":"https:\/\/www.estiv.org\/?page_id=4068"},"modified":"2026-04-09T12:10:48","modified_gmt":"2026-04-09T10:10:48","slug":"estiv-corporate-members","status":"publish","type":"page","link":"https:\/\/www.estiv.org\/membership\/estiv-corporate-members\/","title":{"rendered":"ESTIV CORPORATE MEMBERS"},"content":{"rendered":"\n

Welcome to the European Society of Toxicology In Vitro (ESTIV), where connections thrive and information empowers. As a pivotal hub in the realm of in vitro toxicology across Europe, ESTIV offers unparalleled avenues for companies and institutes seeking recognition and impact in this vital field.<\/p>\n\n\n\n

Our corporate members help to shape the future of innovative toxicology. We are thankful for their ongoing support. <\/h2>\n\n\n\n
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ESTIV connects people and information in the field of in vitro toxicology within Europe. If a company or institute is looking for the right recognition in this field, ESTIV can provide it with the right attention. Basic Corporate Membership (\u20ac500 per year), Silver (\u20ac1000 per year), Gold (\u20ac1500 per year) are offered to interested organisations. For further information, please contact ESTIV secretariat svatkova@guarant.cz <\/p>\n\n\n\n

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Silver sponsor<\/h2>\n\n\n\n
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React4life <\/strong>is an Italian startup\u202fthat developed MIVO\u00ae – Multi In Vitro Organ,\u202fa patented microphysiological system (MPS) able to reproduce portions of the human body improving the reliability of the testing outcome. It can easily accommodate and cultivate 3D human tissues, organoids or biopsies to suit every testing needs. MIVO\u00ae\u202fcan be used as bioreactor, for enhancing tissues conditions and prolonging lifetime, for advanced drug testing assays on 3D tissues, for discovering new therapeutic approaches, and for basic research, without involving animal use.\u202fIt is individually blistered, sterile, disposable, immediately ready-to-use. <\/p>\n\n\n\n

For more information visit: www.react4life.com<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

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Corporate members<\/h2>\n<\/div>\n<\/div>\n\n\n\n
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acCELLerate<\/strong> is a specialist for large-scale production and cryopreservation of highly functional assay ready cells<\/a>. The instant use of cells from a frozen stock became a widely accepted approach which is preferred to the use of continuously passaged cells. Based on 16 years of experience acCELLerate has developed freezing protocols and established well-controlled processes to prepare assay ready Frozen Instant Cells of high quality and robustness. Frozen Instant Cells can be used like a reagent without prior cultivation. acCELLerate provides assay ready cells from multiple cell lines, validated instaCELL bioassay kits, as well as custom cell banks of Frozen Instant Cells with comprehensive documentation to meet specific requirements of the different fields of application.<\/p>\n\n\n\n

For more informatiom visit: w<\/a>ww.accellerate.me<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

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Altertox<\/strong> Academy is a SME (Small Medium Enterprise) with tailor made trainings as main activity. It provides hands-on training in human-relevant alternative methods and technologies for toxicologists, from a 3R perspective (replacement, reduction and refinement). Among other services, Altertox Academy also provides support as work package leader in training for EU calls.<\/p>\n\n\n\n

For more information visit: https:\/\/academy.altertox.be\/<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

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BiomimX is a Spinoff of Politecnico di Milano, pioneer in Organ-on-a-Chip (OoC) technology, dedicated to transforming pharmaceutical drug discovery through clinically relevant in-vitro models. At the core of our innovation is the proprietary uBeat\u00ae platform, which integrates microfluidics, 3D human cell cultures, and controlled mechanical stimulation. This unique approach produces “Beating OoCs” that replicate human pathophysiology with unprecedented precision, offering a superior alternative to traditional animal models that often fail to translate to human outcomes. Our flagship model, uHeart, is a functional heart-on-a-chip recently qualified as a cardiotoxicity predictor with 83.3% sensitivity. The pipeline also includes uKnee, which has successfully supported IND filings for osteoarthritis, alongside models for fibrosis (uScar), gut, lung, and multi-organ systems. By providing both advanced research tools and specialized services, BiomimX enables faster, cost-effective, and ethical drug development, positioning itself as a key leader in the global shift toward predictive non-animal testing.<\/p>\n\n\n\n

For more information visit: <\/a>www.biomimx.com<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

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Epithelix<\/strong> is a leader for in vitro<\/em> assessment of drug efficacy and toxicity on the human respiratory tract. Epithelix has developed unique 3D in vitro<\/em> human airway tissues (MucilAir\u2122; SmallAir\u2122 and AlveolAir\u2122) and testing services for studying airway pathologies like Asthma, Cystic Fibrosis and Chronic Obstructive Pulmonary Diseases, Bacterial and Viral infections. <\/p>\n\n\n\n

For more information visit: www.epithelix.com<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

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EPISKIN<\/strong>, world leader in tissue engineering, offers Human Reconstructed Tissues to the global scientific community – academic and industry – to support research and development activities in Safety and Efficacy. Based in Lyon, France, we partner with cosmetical, pharmaceutical and chemical industries to develop relevant and reliable safety and efficacy tests. Our models are critical tools to speed up Research and Development phases and to shorten the time to market. Some screening tests are already referenced and validated as alternatives to animal use, and others are in the process of validation. Our unique cell culture process allows to industrialize important volumes of in vitro<\/em> models of reconstructed human tissues with well-characterized histology, functionality, and ultrastructure features. The production unit has been designed to deliver every week our clients with thousands of human tissues. We also ensure training and education on how to use our models as alternative methods to animal testing and support our customers and partners in providing a dedicated and customized service.<\/p>\n\n\n\n

For more information visit: https:\/\/www.episkin.com\/Episkin-Academy<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

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The Fraunhofer-Gesellschaft<\/strong>, headquartered in Germany, is the world\u2019s leading applied research organization. With its focus on developing key technologies that are vital for the future and enabling the commercial exploitation of this work by business and industry, Fraunhofer plays a central role in the innovation process. As a pioneer and catalyst for groundbreaking developments and scientific excellence, Fraunhofer helps shape society now and in the future. Founded in 1949, the Fraunhofer-Gesellschaft currently operates 74 institutes and research institutions throughout Germany.<\/p>\n\n\n\n

For more information visit: www.frauhofer.de<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

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MatTek In Vitro Life Science Laboratories<\/strong>, a European subsidiary of MatTek Corporation (USA) produces reconstructed 3D human tissue models in Bratislava, Slovakia since 2011. MatTek develops, validates, and implements animal alternative testing methods and innovative 3D reconstructed human tissue models for more than 3 decades. Our EpiDerm and EpiOcular tissue models are used in regulatory toxicology (OECD, EU guidelines) and address toxicology and efficacy concerns throughout the cosmetics, chemical, pharmaceutical, and household product industries. In addition to these two, there are 11 more ready-to-use, highly reproducible reconstructed 3D human tissue models in the MatTek portfolio. In 2021, MatTek Corporation was acquired by a bioconvergence corporation CELLINK where it continues its mission toward more precise animal-free testing.<\/p>\n\n\n\n

For more information visit: http:\/\/www.mattek.com<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

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ReadyCell <\/strong>is a biotechnological company focused on providing cell-based in vitro tools for the ADME-Tox segment. Our current product portfolio covers a broad spectrum of drug discovery applications for in vitro screening, such as absorption, drug-transporter interactions, and toxicity. <\/em>Furthermore, ReadyCell owns a patented technology that allows the shipment of living plated cells at room temperature, maintaining their viability and cellular characteristics and simplifying logistic times and procedures. Thanks to our well-position network of distributors worldwide, including the United States, India, and Japan, ReadyCell ensures an effective expansion and presence, encompassing over 100 active clients from industry and academia alike.<\/em>

For more information visit: https:\/\/readycell.com\/<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

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The Regulatory Company<\/strong> aims to guarantee product safety and compliance in a rapidly developing context. They act with in dept toxicological and regulatory knowledge and pursue an effective and efficient way of working in cooperation with regulators, authorities, producers, distributors, brand-owners, service providers and other stakeholders.
To add the highest possible value The Regulatory Company contributes to the entire product lifecycle from information management, regulatory and toxicological perspective, by offering and executing complete services, in close and involved partnership with clients. They work fully digital making use of the latest available technology, making sure the experts can be contacted easily and directly.

For more information visit: https:\/\/www.theregulatorycompany.com\/<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

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Founded in 1989 by Christiane Laupie-Koechlin under the honorary presidency of Prof. Th\u00e9odore Monod, the Pro Anima Scientific Committee is a pioneering non-profit organization based in France. Active at the French and European levels, the Committee aims to accelerate the development and consideration of non-animal human-relevant methods to better address the challenges of biomedical research and to improve the risk assessment of chemicals.

The Committee’s main missions are :<\/p>\n\n\n\n