Scientific Work Plan
The in3 work plan endeavours to connect all ESR activities in a
collaborative synergistic way at each step. ESRs will use the same donor
iPSCs and a large overlap of chemicals. The in vitro researchers will collaborate closely with their
I
counterparts on Adverse Outcome Pathway (AOP) development, biokinetic assays and
in silico tool
optimisation. All information will be collected into AOPs for further
modelling and development of quantitative AOPs for each organ.
Additionally, since several different target tissues will be
investigated we will compile this information into an organism-level
systems toxicology model.
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in3 is funded by the
Marie Skłodowska-Curie Action - Innovative Training Network under grant no. 721975.
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