The 54th Congress of the European Societies of Toxicology (EUROTOX) took place in Brussels-Belgium on 2-5 September 2018 and was co-organized by the Belgian Society of Toxicology and Ecotoxicology (BelTox). The theme of the congress was “Toxicology out of the box” and the scientific program highlighted significant developments and achievements in the field of toxicology, including in vitro and in silico toxicology. ESTIV has granted a best poster award, including a prize of 500€ and 1 year free ESTIV membership, during the congress to Timothy Allen from the Centre for Molecular Informatics of the Department of Chemistry at the University of Cambridge-United Kingdom for the poster entitled “Computational approaches for predicting molecular initiating events”. The poster was selected by a jury consisting of ESTIV board members based on originality, complexity, presentation, rationale and relevance to the field of in vitro and in silicotoxicology.