Bas Blaauboer received an MSc in biology and a PhD in toxicology at Utrecht University-The Netherlands. He led a group on in vitro toxicology at Utrecht University-The Netherlands. In 2008, he was appointed the Doerenkamp-Zbinden Chair on Alternatives to Animal Testing in Toxicological Risk Assessment. His research is focused on the use of in vitro toxicity data in combination with computer modelling as tools in risk assessment. He is author or co-author of over 200 scientific papers, editorials and book chapters. He received a number of scientific awards. Since his retirement, he acts as a consultant, giving advice on the implementation of non-animal methods in risk and safety assessment strategies. He is editor of Toxicology in Vitro.
Sandra Coecke is a senior scientist at EURL-ECVAM. In 1989, she earned a Degree of University Engineer Biotechnology followed by PhD degree in Pharmaceutical Sciences. She joined in 1993 the Pharmaceutical Company Janssen Pharmaceutica in Beerse-Belgium, leading the In Vitro Toxicology laboratory. In 1994, she was awarded the European Price from the Foundation for the Substitution of Animal Experimentation in Luxembourg. She published over 100 in vitro toxicological papers. At the EC-JRC, she established international accepted quality standards and good in vitro method practices. She manages and coordinates the activities of the regulatory required European Union Network of Laboratories for the Validation of Alternative Methods (EU-NETVAL), which are 37 quality laboratories across Europe and leads the EU-NETVAL thyroid validation study.
With a background in food sciences engineering obtained in France and a Ph.D. on in vitro neurotoxicity obtained in Switzerland, Chantra Eskes has over 20 years of experience in the development, optimization, validation, peer-review, and regulatory acceptance of alternative methods to animal testing. Working initially at EURL-ECVAM, Chantra then provided consultation services on alternative methods for intergovernmental organizations, regulatory bodies, industry associations, and academia. Her activities contributed among others to the successful validation, peer-review, and international acceptance of over 15 alternative methods and approaches to animal testing. Chantra is the chairwoman of the EURL-ECVAM Scientific Advisory Committee (ESAC) and also acts as a Swiss Nominated Expert for OECD expert groups related to alternative methods to animal experimentation. She has been the president of ESTIV from 2012 to 2016. Finally, she is editor, author, and co-author of over 60 scientific publications, including the following books published by Springer: ‘Validation of Alternative Methods for Toxicity Testing’ (2016) and ‘Alternatives for Dermal Toxicity Testing’ (2017).
Theo de Kok
Theo de Kok is a professor in population-based toxicogenomics affiliated to Maastricht University-the Netherlands, where he is active in the school of Oncology and developmental Biology and the Maastricht Center of Systems Biology. He has a background in toxicological sciences and is a European Registered Toxicologist. His expertise lies in the field of human exposome research and toxicological studies in human cell cultures, particularly liver and colon. His research addresses exposures related to food, environment, drugs and cosmetics. He has been involved in several (inter)national (in vitro) toxicology projects, initiatives and societies.
Arno Gutleb graduated from the University of Veterinary Medicine Vienna-Austria, holds a PhD in Environmental Sciences from Wageningen University-The Netherlands and is a European Registered Toxicologist. He is Distinguished Professor at the University Iuliu Hatieganu at Cluj-Romania and Visiting Professor at the Universidad Andrés Bello at Santiago de Chile-Chile. He is author of more than 180 journal publications. Currently, he is Group Leader Environmental Health at the Luxembourg Institute of Science and Technology.
Helena Kandárová is a senior scientist at CEM, Slovak Academy of Science and at the Faculty of Chemical and Food Technology, STU. Her scientific interest is focusing on the development and validation of in vitro methods. She has been involved in international projects aiming at the validation of 3D reconstructed human tissue models for topical toxicity testing of chemicals, cosmetics, pesticides and medical devices. Helena is a board member of ESTIV, chair of the Slovak National Platform for 3Rs, chair of the EUROTOX communication committee and member of the In2TOX Specialty Section of EUROTOX. She established and led MatTek IVLSL in the EU for 10 years.
Silvia Letasiova is the managing director and senior scientist at MatTek In Vitro Life Science Laboratories at Bratislava-Slovakia. She has a background in biochemistry and microbiology, and holds a doctoral degree in biochemistry. Since 2008, she actively works on the development and validation of assays aiming at the reduction and replacement of in vivo testing. She is a member of US SOT, ESTIV, SETOX and EUSAAT. She is a co-author of more than 30 publications and has presented the innovative science in more than 75 oral and poster presentations at national and international meetings.
Jochem Louisse works as a toxicologist at Wageningen Food Safety Research-The Netherlands. He has a background in biology, holds a doctoral degree in Toxicology and is a European Registered Toxicologist. In his research, he combines in vitro toxicology data and physiologically-based kinetic modelling to predict in vivo toxicity. Also, he works on the application of mode-of-action-based bioassays to detect and prioritize chemicals in food.
Jan Markus is production manager and senior scientist at MatTek In Vitro Life Science Laboratories at Bratislava-Slovakia. He has a background in molecular biology and virology, and holds a doctoral degree in experimental oncology. He is responsible for the production and further development of reconstructed tissue models of small intestine. Also, he is actively involved in the development and validation of new tests aimed at the reduction of in vivo testing. His areas of expertise include cell and tissue cultures, molecular biology, transcriptional gene regulation and oncology.
Philippe Vanparys is biologist and obtained his Master in Sciences at the Free University Ghent-Belgium and PhD in Sciences at the Catholic University Louvain-La-Neuve-Belgium. During his 30 year career at Janssen Phamaceutica-Belgium, he was Senior Director Genetic and In vitro Toxicology and Senior Director Mechanistic Toxicology. The last ten years, he was guest professor at the Catholic University Leuven-Belgium. He is European Registered Toxicologist and was involved in several (inter)national genetic and in vitro toxicology societies, and in several workgroups at ECVAM. At GENTOXICON BVBA-Belgium, he still consults companies for issues in genetic toxicology.
Mathieu Vinken is associate professor affiliated to the Vrije Universiteit Brussel-Belgium. He has a background in pharmaceutical sciences, holds a doctoral degree in experimental in vitro toxicology and is a European Registered Toxicologist. He is President of the European Society of Toxicology In Vitro. He is author of more than 150 journal publications. He is associate editor of Toxicology In Vitro and Archives of Toxicology, and European editor of Applied In Vitro Toxicology.