Scientific papers and book chapters

European Society of Toxicology In Vitro > Scientific papers and book chapters

2023

CALONI, Francesca – DE ANGELIS, Isabella – GRIBALDO, Laura – HEINONEN, Tuula – KANDAROVA, Helena – KRAL, Vivian – LETAŠIOVÁ, Silvia – SILLÉ, Fenna – SMIRNOVA, Lena – VINARDELL, Maria Pilar – HARTUNG, Thomas. Women in Alternatives. In ALTEX : Alternatives to Animal Experimentation, 2023, vol. 40, no. 3, pp. 545-548. . ISSN 1868-596X. https://doi.org/10.14573/altex.2303211


VISKUPIČOVÁ, Jana – REZBÁRIKOVÁ, Petronela – KOVÁČIKOVÁ, Lucia – KANDAROVA, Helena – MÁJEKOVÁ, Magdaléna. Inhibitors of SARS-CoV-2 main protease: Biological efficacy and toxicity aspects. In Toxicology in vitro: the official journal of the European Society for Toxicology in Vitro, 2023, vol. 92, art. no. 105640. ISSN 0887-2333. Dostupné na: https://doi.org/10.1016/j.tiv.2023.105640

Naik NN, Vadloori B, Poosala S, Srivastava P, Coecke S, Smith A, Akhtar A, Roper C, Radhakrishnan S, Bhyravbhatla B, Damle M, PullaVK, Hackethal J, Horland R, Li AP, Pati F, Singh MS, Occhetta P, Bisht R, Dandekar P, Bhagavatula K, Pajkrt D, Johnson M, Weber T, Huang J, Hysenaj L, Mallar B, Ramray B, Dixit S, Joshi S, and Kulkarni K (2023). Advances in animal models and cutting-edge research in alternatives: proceedings of the third international conference on 3Rs research and progress, Vishakhapatnam, 2022. Alternatives to Laboratory Animals 51(4): 263-288. https://doi:10.1177/02611929231180428

Turner J, Pound P, Owen C, Hutchinson I, Hop M, Chau DYS, Barrios Silva LV, Coleman M, Dubourg A, Harries LW, Hutter V, Kenna JG, Lauschke VM, Neuhaus W, Rper C, Watkins PB, Welch J, Alvarez LR and Taylor K (2023). Incorporating new approach methodologies into regulatory nonclinical pharmaceutical safety assessment. ALTEX 40(3): 519-533. doi: 10.14573/altex.2212081.

Wallace J, Jackson GR, Kaluzhny Y, Ayehunie S, Lansley AB, Roper C, and Hayden PJ. (2023). Evaluation of in vitro rat and human airway epithelial models for acute inhalation toxicity testing. Toxicological Sciences 194 (2); 178‑190. doi: 10.1093/toxsci/kfad058.

2022

Hummer J, Birngruber T, Sinner F, Page L, Toner F, Roper CS, Moore, DJ, Baker MB, and Boncheva Bettex M (2022). Optimization of topical formulations using a combination of in vitro methods to quantify the transdermal passive diffusion of drugs. International Journal of Pharmaceutics. https://doi.org/10.1016/j.ijpharm.2022.121737.

CALONI, Francesca – INTROZZI, Olga – CAZZANIGA, Alessandra – BUZANSKA, Leonora – GUTLEB, Arno C. – KANDAROVA, Helena – CERIOTTI, Laura – RANALDI, Giulia – RASHIDI, Hassan – WILFLINGSEDER, Doris. Third Virtual Summer School 3Rs for ONE Science: Alternative methods: From complexity to predictivity : meeting report. In ALTEX : Alternatives to Animal Experimentation, 2022, vol. 39, no. 4, p. 710-711. https://doi.org/10.14573/altex.2207112 

Kluxen FM, Roper CS, Jensen SM and Koenig CM (2022). Characterizing local acute irritation properties of captan and folpet with new approach methods. Applied In Vitro Toxicology 8 (3); 83-101. https://doi.org/10.1089/aivt.2022.0004

NEUHAUS, Winfried – REININGER-GUTMANN, Birgit – RINNER, Beate – WILFLINGSEDER, Doris – JÍROVÁ, Dagmar – KEJLOVÁ, Kristína – KANDAROVA, Helena – SPIELMANN, Horst. The Current Status and Work of Three Rs Centres and Platforms in Europe. In Alternatives to Laboratory Animals (ATLA) : Fund for the Replacement of Animals in Medical Experiments, 2022, vol. 50, no. 6, p. 381-413. ISSN 0261-1929.  https://doi.org/10.1177/02611929221140909 

NEUHAUS, Winfried – REININGER-GUTMANN, Birgit – RINNER, Beate – PLASENZOTTI, Roberto – WILFLINGSEDER, Doris – KANDAROVA, Helena. The rise of three Rs centres and platforms in Europe. In Alternatives to Laboratory Animals (ATLA), 2022, vol. 50, no. 2, p. 90-120. ISSN 0261-1929.  https://doi.org/10.1177/02611929221099165 

Roper CS, Hargrove MM, Sullivan K and Wolf D (2022). Case study on the use of an Integrated Approach for Testing and Assessment (IATA) for New Approach Methodology (NAM) for refining inhalation risk assessment from point of contact toxicity of the pesticide, chlorothalonil. ENV/CBC/MONO(2022)31. OECD Environment, Health and Safety Publications Series on Testing and Assessment No. 367.  https://www.oecd.org/officialdocuments/publicdisplaydocumentpdf/?cote=env/cbc/mono(2022)31&doclanguage=en

SEIDLE, Troy – KANĎÁROVÁ, Helena – HARTUNG, Thomas – LEIST, Marcel – NEUHAUS, Winfried – SPIELMANN, Horst – ROVIDA, Costanza. Open letter: Selection of a new Executive Director of the European Chemicals Agency (ECHA) provides an opportunity for the EU to lead in the field of chemicals management and implementation of innovative science = Selection of a new Executive Director of the European Chemicals Agency (ECHA) provides an opportunity for the EU to lead in the field of chemicals management and implementation of innovative science. In ALTEX : Alternatives to Animal Experimentation, 2022, vol. 39, no. 1, p. 149-150. ISSN 1868-596X. https://doi.org/10.14573/altex.2110271 

SONAWANE, Akshay – VADLOORI, Bharadwaja – POOSALA, Suresh – KANĎÁROVÁ, Helena – KULKARNI, Mandar – OLAYANJU, Adedamola – DEY, Tuli – SAXENA, Uday – SMIRNOVA, Lena – KANDA, Yasunari – REDDY, Jaganmohan – DRAVIDA, Subhadra – BISWAS, Saikat – VINKEN, Mathieu – GETTAYACAMIN, Montip – AHLUWALIA, Arti – MONDINI, Franco – BHATTACHARYA, Somshuvra – KULKARNI, Pushkar – JACOBSEN, Kirsten Rosenmay – VANGALA, Subrahmanyam – MILLÁS, Ana Luiza. Advances in animal models and cutting-edge research in alternatives: Proceedings of the Second nternational Conference on 3Rs research and progress, Hyderabad, 2021. In Alternatives to Laboratory Animals (ATLA), 2022, vol. 50, no. 2, p. 156-171. ISSN 0261-1929. https://doi.org/10.1177/02611929221089216 

2021

CALONI, Francesca – CAZZANIGA, Alessandra – COCCINI, Teresa – GUTLEB, Arno C. – KANDAROVA, Helena – CERIOTTI, Laura – RASHIDI, Hassan – SAMBUY, Yula – VON AULOCK, Sonja – WILFLINGSEDER, Doris. Second Virtual Summer School: Alternative Methods in Science: Towards Model Complexity : meeting report. In ALTEX : Alternatives to Animal Experimentation, 2021, vol. 38, no. 3, p. 510-512. https://doi.org/10.14573/altex.2106221 

JANOUŠEK, Stanislav – VLKOVÁ, Alena** – JÍROVÁ, Gabriela – KEJLOVÁ, Kristína – KRSEK, Daniel – JÍROVÁ, Dagmar – KANĎÁROVÁ, Helena – WITTLINGEROVÁ, Zdenka – HEINONEN, Tuula – MANNERSTROM, Marika – MALÝ, Marek. Qualitative and Quantitative Analysis of Certain Aspects of the Cytotoxic and Genotoxic Hazard of Hospital Wastewaters by Using a Range of In Vitro Assays. In ATLA-Alternatives to Laboratory Animals : Fund for the Replacement of Animals in Medical Experiments, 2021, vol. 49, no. 1-2, p. 33-48. ISSN 0261-1929.  https://doi.org/10.1177/02611929211004956 

Kandarova H . Alternative methods to animal experimentation and their role in modern toxicology. In Toxicological Risk Assessment and Multi-System Health Impacts from Exposure. – Elsevier Inc., Academic Press, 2021, part 1, chapter 2, P. 13-22. ISBN 978-0-323-85215-9.  https://doi.org/10.1016/B978-0-323-85215-9.00047-7

Kandarova H, Hayden P (2021) Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development. In Handbook of Experimental Pharmacology. – Springer Nature, 2021, 2021, vol. 265, p. 57-71. ISSN 0171-2004. https://doi.org/10.1007/164_2020_417

Laperrouze J. (2021) How Non-Animal Testing Can Reshape Health and Environment Policies. Vox Europ link 

Lauschke K, Treschow AF, Rasmussen MA, Davidsen N, Holst B, Emnéus JK, Taxvig C and Vinggaard AM (2021) Creating a human NKX2.5 reporter stem cell line for developmental toxicity testing. Arch Toxicol p.1-12 doi: 10.1007/s00204-021-03018-y   

Lauschke K, Volpini L, Liu Y, Vinggaard AM, Hall VJ (2021) A comparative assessment of marker expression between cardiomyocyte differentiation of human iPSCs and the developing pig heart. Stem Cells Dev 30(7):374-385 doi: 10.1089/scd.2020.0184   

Plaza A, Toner F, Harris J, Ottersbach P, Roper Cand Mahony C (2021). Support for regulatory assessment of percutaneous absorption of retronecine-type pyrrolizidine alkaloids through human skin. Support for regulatory assessment of percutaneous absorption of retronecine-type pyrrolizidine alkaloids through human skin. Planta Medica 88 (2); 144-151. https://doi.org/10.1055/a-1505-8524.

Rodríguez-Carrillo A, Rosenmai AK, Mustieles V, Couderq S, Fini J-B, Vela-Soria F, Molina-Molina JM, Ferrando-Marco P, Bonefeld-Jorgensen EC, Olea N, Vinggaard AM, Fernández MF (2021) Assessment of chemical mixtures using biomarkers of combined biological activity: Screening study with human placentas. Reprod Toxicol 100:143-154 doi: 10.1016/j.reprotox.2021.01.002   

Singh B, Abdelgawad ME, Ali Z, Bailey J, Budyn E, Civita P, Clift MJD, Connelly JT, Constant S, Hittinger M, Kandarova H, Kearns VR, Kiuru T, Kostrzewski T, Kress S, Durban VM, Lehr CM, McMillan H, Metz JK, Monteban V, Movia D, Neto C, Owen C, Paasonen L, Palmer KA, Pilkington GJ, Pilkington K, Prina-Mello A, Roper C, Sheard J, Smith S, Turner JE, Roy I, Tutty MA, Velliou E, Wilkinson JM (2021). Towards more predictive, physiological and animal-free in vitro models: advances in cell and tissue Culture 2020 conference proceedings. Alternatives to Laboratory Animals 2021 Jul 6:2611929211025006. doi: 10.1177/02611929211025006. Epub ahead of print. PMID: 34225465.

Spielmann H, Kandarova H (2021). Integration of Advanced Technologies into Regulatory Toxicology. In Regulatory Toxicology. 2nd edition. Springer Nature Switzerland AG, 2021, 14 p. ISBN 978-3-030-57498-7. https://doi.org/10.1007/978-3-642-36206-4_34-2

Spielmann H, Kandarova H (2021). International Regulation of Toxicological Test Procedures. In Regulatory Toxicology. 2nd edition. Springer Nature Switzerland AG, 2021, 10 p. ISBN 978-3-030-57498-7. https://doi.org/10.1007/978-3-642-36206-4_41-2

Weber T, Wirths F, Brakebusch N, van der Valk J (2021) Reply to comment ‘Animal welfare and ethics in the collection of fetal blood for the production of fetal bovine serum’, ALTEX 38(2): 324-326 doi: 10.14573/altex.2103191 

Welch J, Wallace J, Lansley A and Roper (2021). Evaluation of the toxicity of sodium dodecyl sulphate (SDS) in the MucilAir™ human airway model in vitro. Regulatory Toxicology and Pharmacology 125; 105022. https://doi.org/10.1016/j.yrtph.2021.105022.

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