The annual EURL ECVAM status report describes research, development and validation activities, as well as initiatives that promote the regulatory use and international adoption of non-animal methods and approaches and their dissemination in the regulatory and research arenas. EU policies and legislation call for innovative and more efficient ways of safety testing and chemical risk assessment that do not depend on animal testing. Advanced technologies such as computational models, in vitro methods and organ-on-chip devices are being developed, evaluated and integrated to translate mechanistic understanding of toxicity into safety testing strategies. The ultimate goal is to achieve better protection of human health and the environment while supporting EU innovation and industrial competitiveness, without the use of animals. The development and use of non-animal models and methods are also essential for advancing basic, applied and translational research. Education also plays an essential role in enabling a shift to non-animal methods through the introduction of the Three Rs (Replacement, Reduction and Refinement of animal use in science) into secondary school curricula and programmes of higher education.
May ESTIV-ASCCT Webinar: New Approach Methods in genotoxicity and mechanistic toxicity testing for the animal-free safety assessment of novel pharmaceuticals and chemicals
Every year, large numbers of new compounds are being developed for a wide range of purposes…..
The new Biomedical research report from ECVAM: Tackling neurodegenerative diseases with more human relevant research
To promote more human relevant research, the JRC’s EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) led a study to review advanced non-animal models used in the field of neurodegenerative diseases, specifically for Parkinson’s and Alzheimer’s.
ESTIV Corporate member’s event: EPISKIN ACADEMY Webinar
The second EPISKIN webinar is focusing on the theme eye irritation and Integrated Approaches to Testing and Assessment (IATA) for Serious Eye Damage and Eye Irritation for regulatory toxicology…